Table 1. Clinical Characteristics in Patients With Reduced and Normal CFR (Mean±SD or Number [%])
All Patients (n=371)CFR ≤2.0 (n=76)CFR >2.0 (n=295)P Value
Age, y62.2±8.764.5±10.061.7±8.30.027
Sex (male), n174 (47)46 (61)128 (43)0.008
BMI, m2/kg26.2±3.826.1±3.926.2±3.80.87
Diabetes mellitus, n46 (12%)13 (17%)33 (11%)0.17
Hypertension, n47 (12%)10 (13%)37 (13%)0.89
Smoking, n181 (49%)45 (59%)136 (46%)0.040
Hypercholesterolemia, n184 (50%)42 (55%)142 (48%)0.24
Ejection fraction, %63±1259±1364±110.001
Laboratory data
ApoB/ApoA1 ratio0.7±0.20.7±0.20.7±0.20.80
Triglycerides, mmol/L1.4±0.91.6±1.21.4±0.80.084
Total cholesterol, mmol/L5.3±1.35.2±1.35.3±1.30.51
High‐density lipoprotein, mmol/L1.5±0.41.4±0.41.5±0.40.52
Medication
β‐blockers, n191 (52%)48 (63%)143 (48%)0.022
Statins, n165 (45%)39 (51%)126 (43%)0.18
ACE inhibitors, n91 (25%)26 (34%)65 (22%)0.028
Aspirin, n195 (53%)48 (63%)150 (51%)0.055
Clopidogrel, n24 (7%)5 (7%)19 (6%)0.97
  • ACE indicates angiotensin‐converting enzyme; Apo, apolipoprotein; BMI, body mass index; CFR, coronary flow reserve.