Table 1. Characteristics and Laboratory Data of ApoE−/− Mice (Experiment 1)
ParameterApoE−/− Mice (C57/B6)
13W Control17W Control 0 μg/kg per hour17W KP‐10 5 μg/kg per hour17W KP‐10 12.5 μg/kg per hour
N3545
Body weight, g27.7±0.7630.4±0.60a29.8±0.8529.2±0.58
Food intake, g/dayNE5.9±0.46.4±0.46.3±0.4
Systolic BP, mm Hg109.0±4.5105.0±1.8101.5±4.8104.1±1.6
Diastolic BP, mm Hg89.0±7.085.4±1.081.1±4.083.3±2.7
Total cholesterol, mg/dL322.0±15.81705.5±116.9a1714.9±148.5a1776.6±53.2a
Glucose, mg/dL246.2±73.3353.4±37.0231.3±38.1312.4±44.1
KP‐10, ng/mL5.65±2.145.85±2.216.37±2.1619.54±5.01b
  • Mean±SEM. ApoE−/− indicates apolipoprotein E deficient; BP, blood pressure; KP‐10, kisspeptin‐10; NE, not examined.

  • a P<0.05 vs 13W control.

  • b P<0.05 vs 17W control.