Table 2. Characteristics and Laboratory Data of ApoE−/− Mice (Experiment 2)
ParameterApoE−/− Mice (BALB/c)
13W Control17W Control 0 μg/kg per hour17W KP‐10 12.5 μg/kg per hour17W KP‐10+P234
N7101011
Body weight, g26.7±1.228.0±0.829.2±1.228.3±0.7
Food intake, g/dayNE5.0±0.65.4±0.35.2±0.5
Systolic BP, mm Hg93.4±1.092.8±1.394.2±1.293.3±1.6
Diastolic BP, mm Hg72.6±1.071.8±1.474.3±1.073.7±1.5
Total cholesterol, mg/dL575.0±82.42140.3±52.0*2028.6±42.7*1930.0±112.4*
Glucose, mg/dL199.3±35.4279.8±21.5265.0±20.2282.6±28.0
KP‐10, ng/mL0.4±0.10.6±0.11.6±0.22.4±0.4
  • Mean±SEM. ApoE−/− indicates apolipoprotein E deficient; BP, blood pressure; KP‐10, kisspeptin‐10; NE, not examined.

  • *P<0.05 vs 13W control.

  • P<0.005; P<0.0001 vs 17W control.