Table 2. The Impact of Hemoglobin Levels on Mortality at Different Time Points (Logistic Regression)
VariableHemoglobin quintileEvents
12345
Male ischemic
Number635675667644677
Inpatient2.64 (1.83–3.81)1.56 (1.08–2.25)1.001.59 (1.06–2.38)1.62 (1.08–2.42)511
1 month2.99 (2.06–4.34)1.74 (1.19–2.53)1.001.55 (1.03–2.34)1.79 (1.19–2.68)488
3 months3.09 (2.24–4.25)1.34 (0.96–1.85)1.001.18 (0.82–1.69)1.37 (0.96–1.95)674
6 months2.92 (2.16–3.94)1.37 (1.01–1.85)1.001.05 (0.75–1.46)1.16 (0.83–1.63)796
1 year2.90 (2.18–3.86)1.43 (1.08–1.90)1.001.17 (0.86–1.59)1.17 (0.86–1.60)971
Male hemorrhagic
Number8310910387131
Inpatient1.23 (0.58–2.60)0.83 (0.42–1.65)1.000.86 (0.39–1.86)1.05 (0.53–2.09)176
1 month1.22 (0.59–2.51)0.92 (0.48–1.78)1.000.81 (0.39–1.70)0.93 (0.48–1.80)173
3 months1.16 (0.55–2.42)0.67 (0.34–1.30)1.000.76 (0.38–1.57)0.68 (0.35–1.57)200
6 months1.65 (0.77–3.55)0.81 (0.41–1.60)1.000.78 (0.38–1.62)0.73 (0.38–1.41)221
1 year1.97 (0.92–4.22)0.81 (0.42–1.58)1.000.73 (0.35–1.51)0.79 (0.41–1.51)229
Female ischemic
Number698748700752755
Inpatient1.47 (1.08–1.98)1.05 (0.77–1.43)1.001.39 (1.01–1.90)1.20 (0.88–1.63)792
1 month1.48 (1.09–2.01)1.16 (0.85–1.58)1.001.23 (0.89–1.69)1.26 (0.92–1.73)733
3 months1.70 (1.28–2.25)1.16 (0.87–1.54)1.001.34 (1.00–1.79)1.19 (0.89–1.58)1007
6 months1.86 (1.42–2.44)1.22 (0.93–1.60)1.001.44 (1.09–1.89)1.26 (0.96–1.67)1159
1 year1.86 (1.44–2.41)1.23 (0.96–1.59)1.001.29 (0.99–1.68)1.13 (0.87–1.46)1328
Female hemorrhagic
Number72100132127118
Inpatient2.56 (1.23–5.32)0.80 (0.41–1.57)1.000.80 (0.54–1.81)1.35 (0.74–2.47)229
1 month2.61 (1.31–5.36)0.80 (0.42–1.55)1.001.12 (0.62–2.01)1.46 (0.81–2.63)226
3 months2.26 (1.10–4.64)0.88 (0.47–1.67)1.000.94 (0.53–1.68)1.22 (0.68–2.19)256
6 months2.02 (0.98–4.16)0.97 (0.52–1.82)1.000.80 (0.45–1.42)1.22 (0.68–2.18)278
1 year2.59 (1.23–5.44)1.20 (0.64–2.25)1.000.95 (0.54–1.68)1.35 (0.75–2.41)292
  • The cutoff points for the quintiles are as follows: male: 12.4, 13.8, 14.6, and 15.6 g/dL; female: 11.7, 12.8, 13.6, and 14.5 g/dL. The variables adjusted for were age, Oxford Community Stroke Project classification, prestroke Rankin Scale score, prior antithrombotic use, coronary heart disease, previous stroke, congestive heart failure, atrial fibrillation, hypertension, hyperlipidemia, diabetes mellitus, peripheral vascular disease, chronic obstructive pulmonary disease, chronic kidney disease, falls, malignancy, dementia, gastrointestinal bleeding, and peptic ulcer. We also adjusted for International Normalized Ratio in patients with hemorrhagic stroke. The International Normalized Ratio was included as a dichotomous categorical variable: <1.40 versus ≥1.40. Data for the time points 7 and 14 days were removed for brevity. Mean ages for the male quintiles were 82.80, 80.48, 78.49, 78.09, and 78.38 years for quintiles 1–5, respectively. Mean ages for female quintiles were 83.04, 81.81, 80.45, 78.96, and 78.06 years for quintiles 1–5, respectively.