Table 7.

Effect of Diets on Lipoprotein Subclasses (Cholesterol Concentration From VAP Test)

Baseline AAD (n=45)LF (n=43)MF (n=42)AV (n=43)Treatment Effect (P Value)
LDL‐C, mg/dL
LDL121.3±1.219.4±1.1a18.4±0.9a,b*17.9±1.0b*0.03
LDL229.7±2.024.7±2.5*25.2±2.1*25.4±2.2*0.6
LDL344.5±2.442.2±2.3a,b43.4±1.9b40.0±2.0a*0.01
LDL410.4±1.312.6±1.6a*11.2±1.4a,b10.5±1.3b0.04
LDL1+251.0±2.844.1±3.3*43.6±2.7*43.2±2.9*0.9
LDL3+455.0±3.354.9±3.5a54.6±3.0a50.5±3.1b*0.01
LDL peak max time, s117.0±0.5115.8±0.6*116.2±0.5*116.4±0.60.4
HDL‐C, mg/dL
HDL211.6±0.710.5±0.6*10.9±0.6*10.8±0.6*0.6
HDL336.9±1.134.2±0.9a*36.1±1.0b36.0±1.0b0.01
VLDL‐C, mg/dL
VLDL1+29.9±0.511.3±0.8a*9.5±0.5b9.1±0.5b<0.0001
VLDL313.3±0.414.2±0.5a*13.1±0.5b12.6±0.4b<0.0001
IDL‐C, mg/dL
IDL14.3±0.34.7±0.3a*4.2±0.3b3.9±0.2b<0.0001
IDL211.4±0.511.1±0.5a10.5±0.6a,b9.8±0.5b*0.0005
Remnant Lp, mg/dL29.0±1.130.0±1.1a*27.8±1.2b26.3±1.0b*<0.0001
  • All values are means±SEMs. AAD indicates average American diet; AV, avocado diet; HDL, high‐density lipoprotein; IDL‐C, intermediate‐density lipoprotein cholesterol; LDL, low‐density lipoprotein; LF, lower‐fat diet; MF, moderate‐fat diet; Remnant Lp, lipoprotein remnants; VAP, vertical auto profile; VLDL‐C, very‐low‐density lipoprotein cholesterol.

  • * Significant change compared to baseline AAD, P<0.05; Values in diet treatments with different superscript letters (a/b) are significantly different (Tukey post‐hoc test by SAS, P<0.05).