Preterm Delivery and Future Risk of Maternal Cardiovascular Disease: A Systematic Review and Meta‐Analysis
Jump to comment
- Published on January 25, 2018RE: Wu, et al., Identify Consequences of High Maternal Testosterone and Early Loss of Testosterone
- James M. Howard, Biologist, Independent
I suggest the basis of the findings of Wu, et al., is high maternal testosterone followed by low testosterone in later adulthood.
That is, high maternal testosterone causes preterm delivery ("Explanation of Preterm and Reduced Growth and Development," at: http://anthropogeny.com/Preterm%20and%20Reduced%20Growth%20and%20Develop... ).
It is my hypothesis that the biological secular trend, the increase in size and earlier puberty in children, is caused by high maternal testosterone. Human evolution is selecting females of higher testosterone because of increased libido. ("Androgens in Human Evolution," Rivista di Biologia / Biology Forum 2001; 94: 345-362. If your library does not subscribe to "Rivista ... ," you may find this at: http://anthropogeny.com/Androgens%20in%20Human%20Evolution.htm .) As increased testosterone becomes excessive, maternal testosterone causes increased, adverse pregnancy outcomes.
As testosterone increases and peaks earlier, the peak of testosterone is skewed to the left which produces an earlier decrease in testosterone in later adulthood. The literature supports low testosterone involvement in increased cardiovascular disease.Competing Interests: None declared.